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However, they should not be used in lieu for the use of explanation trials.<br><br>The idea of pragmatism is controversial and there are doubts about whether pragmatic trials can be used to replace explanation tests or if they are an alternative to them. Schwartz and Lellouch1 suggested the distinction between explanation studies, which confirm the validity of a physiological or clinical hypothesis, as well as pragmatic trials, which inform policy and practice decision-making. They also suggested a framework for pragmatic trials, called PRECIS.2 This tool sought to define the features of a practical trial, including the recruitment process, the design and implementation of the intervention, and the follow-up.<br><br>The number of pragmatic trials is increasing. A recent Medline search using the words pragmatic and  [https://git.noerden.app/pragmaticplay2530 프라그마틱 체험] naturalistic, which was restricted to randomised controlled trials (RCTs), returned 34 articles. These are shown in red on Figure 2. This suggests that the health sciences community is becoming more aware of the importance of pragmatic thinking. It is important to keep in mind that the majority of these trials were conducted in primary care settings.