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Trials designed to inform clinical practice in the real world are referred to as pragmatic trials. They are often characterized as a focus on the practical aspects of study design, including the recruitment process and consent, adhering and the use of routinely available equipment.

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A pragmatic study that involves various investigators and participants from different geographical areas is the Home Blood Pressure Management study (HBPM). This type of heterogeneity is essential for pragmatic trials to be valid, and 프라그마틱 이미지 it also helps to reduce the chance of bias in the results. However excessive heterogeneity could lead to problems with the design of the trial.

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Legality

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Pragmatic trials are designed to replicate real-life settings and achieve maximum external validity. Usually, 프라그마틱 슬롯 체험 they are ordered by policymakers and practitioners to help guide their decisions. They can also be a great method of determining the cause-effect relationship between an intervention and its results. They should not, however be used to replace explanation studies.

The concept of pragmatism is controversial and there are concerns about whether pragmatic trials should be used to replace explanatory trials or complement them. Schwartz and Lellouch1 made the distinction between explanation studies, which prove the validity of a physiological or clinical hypothesis, as well as pragmatic trials that aid in policy and practice decision-making. They also suggested the framework for pragmatic trials, called PRECIS.2 This tool was designed to define the features of a pragmatic study that include the recruitment process, the design and 프라그마틱 무료체험 슬롯버프 implementation of the intervention, as well as monitoring.

There is an encouraging trend in the number of pragmatic trials published. A recent Medline search using the words pragmatic and naturalistic, limited to randomised controlled trials (RCTs), returned 34 articles. They are displayed in red on Figure 2. This indicates that the health sciences community has become more aware of the importance of pragmatism. However, it is important to note that the majority of these trials were conducted in primary care settings.