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Studies designed to provide insight into clinical practice in the real world are called pragmatic trials. They are often described as a focus on the practical aspects of study design, including recruitment and consent, adherence and the use routinely available equipment.
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A practical trial that employs a variety investigators and includes participants from different geographical areas is the Home Blood Pressure Management study (HBPM). This kind of heterogeneity, that is crucial for a pragmatic trial to be reliable and 프라그마틱 슬롯 조작 무료 프라그마틱슬롯 (pageoftoday.Com) lessen the chance of bias, is also necessary. However, too much heterogeneity, can cause problems with the trial design.
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Pragmatic trials are designed to replicate real-life settings and achieve maximum external validity. They are typically ordered by policymakers and practitioners to guide their decisions. They can also be used to assess the causal relationship between an intervention and its results. However, they should not be used to replace explanation studies.
The idea of pragmatism is controversial, and there are questions about whether pragmatic trials can replace tests for explanations or if they should serve as an addition to them. Schwartz and Lellouch1 suggested an distinction between explanation-based studies, which support the validity of a physiological or clinical hypothesis, and pragmatic trials that aid in policy and practice decision-making. They also suggested a framework for pragmatic trials, which they called PRECIS.2 This tool attempted to define the elements of a practical trial which includes the recruitment process, the design and implementation of the intervention, as well as follow-up.
The number of pragmatic trials is increasing. A recent Medline query that used the words pragmatic and naturalistic, limited to randomised controlled trials (RCTs), returned 34 articles. They are displayed in red on Figure 2. This is an indication that the health science community is becoming more acquaint to the issue of pragmatic thinking. It is important to remember that the majority of these studies were conducted in primary care settings.